Featured Episodes

Textiles as Tech, Science, Math, Culture, or Civilization

Virginia Postrel and Sonal Chokshi

AI, WebRTC, Crypto, and Full Stack Startups

Elad Gil, Sep Kamvar, and Chris Dixon

Feedback Loops — Company Culture, Change, and DevOps

Nicole Forsgren, Jez Humble, and Sonal Chokshi

Latest Episodes

The Common Thread of All Technology: Monitoring the Situation, Ep.1

Eddie Lazzarin, Katherine Boyle, and Erik Torenberg

From Vibe Coding to Vibe Researching: OpenAI’s Mark Chen and Jakub Pachocki

Jakub Pachocki, Mark Chen, Anjney Midha, and Sarah Wang

Software finally eats services - Aaron Levie

Martin Casado, Steven Sinofsky, Erik Torenberg, and Aaron Levie

America's Autism Crisis and How AI Can Fix Science with NIH Director Jay Bhattacharya

Dr. Bhattacharya, Scientific Research, Public health, grants, funding, Autism Research, Drug Discovery, Jorge Conde, Vineeta Agarwala, and Erik Torenberg

Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government vs. China

Guido Appenzeller, Sarah Wang, and Dylan Patel

Charlie Kirk and the Rise of Political Violence

Konstantin Kisin, Bari Weiss, and Katherine Boyle

The Death of Search: How Shopping Will Work In The Age of AI

Alex Rampell, and Justine Moore

How OpenAI Built Its Coding Agent

Alexander Embiricos, and Anjney Midha

Faster Science, Better Drugs

Jorge Conde, Erik Torenberg, and Patrick Hsu

Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy

Lenny Rachitsky, and Ben Horowitz

Inside the $13T Mortgage Machine

Tim Mayopoulos, Andrew Wang, Mike Yu, and Angela Strange

Chris Dixon on How to Build Networks, Movements, and AI-Native Products

Chris Dixon, and Anish Acharya

Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics

Erik Torenberg, and Mark Cuban

The Little Tech Agenda for AI

Matt Perault, Collin McCune, and Erik Torenberg

Building APIs for Developers and AI Agents

Jennifer Li, and Alex Rattray

How to Be Free: Shaka Senghor, Oprah Winfrey, Ben Horowitz

Oprah Winfrey, Ben Horowitz, and Shaka Senghor

Is Non-Consensus Investing Overrated?

Leo Polovets, and Martin Casado

Jack Altman & Martin Casado on the Future of VC

martin casado, and jack altman

Chris Best of Substack on the Future of Media

Katherine Boyle, Andrew Chen, Chris Best, and Erik Torenberg

Katherine Boyle on Shawn Ryan

Shawn Ryan, and Katherine Boyle

Monopolies vs Oligopolies in AI

Harry Stebbings, and Martin Casado

The Top 100 Most Used AI Apps in 2025

Justine Moore, and Olivia Moore

Aaron Levie and Steven Sinofsky on the AI-Worker Future

Aaron Levie, Martin Casado, Steven Sinofsky, and Erik Torenberg

Ben Horowitz on How a16z Was Built

Erik Torenberg, and Ben Horowitz

AI and Accelerationism with Marc Andreessen

James Ellis, and Marc Andreessen

Can AI Fix Housing and Healthcare Affordability?

Tony Stoyanov, ai, artificial intelligence, housing, automation, healthcare, regulation, Alex Immerman, and Erik Torenberg

Oren Cass & Noah Smith Debate the True Impact of Tariffs

Oren Cass, Erik Torenberg, and Noah Smith

Dylan Patel: GPT-5, NVIDIA, Intel, Meta, Apple

Dylan Patel, Erin Price-Wright, Guido Appenzeller, and Erik Torenberg

Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building

Jack Parker-Holder, Shlomi Fruchter, Marco Mascorro, Anjney Midha, and Justine Moore

The State of American AI Policy: From ‘Pause AI’ to ‘Build’

Anjney Midha, Erik Torenberg, and Martin Casado

H20s to China + 15% with Chris Miller and Lennart Heim

Chris Miller, and Lennart Heim

Grok, Genie 3, GPT-5 & the Rise of Vibe Coding

Olivia Moore, and Justine Moore

Alex Danco on Speechwriting, Blogging, and Giving Founders Power

Alex Danco, Jordi Hays, and John Coogan

Steven Sinofsky & Balaji Srinivasan on the Future of AI, Tech, & the Global World Order

Balaji Srinivasan, Erik Torenberg, and Steven Sinofsky

Marc Andreessen: Why Perfect Products Become Obsolete

TBPN, John Coogan, Jordi Hays, and Marc Andreessen

GPT-5 and Agents Breakdown – w/ OpenAI Researchers Isa Fulford & Christina Kim

Christina Kim, Isa Fulford, Erik Torenberg, and Sarah Wang

How to Build a Successful Company in an Era of Disruption

Jeetu Patel, Raghu Raghuram, and Martin Casado

Dwarkesh and Noah Smith on AGI and the Economy

Dwarkesh Patel, and Noah Smith

Balaji on How Tech Truly Wins Media

Balaji Srinivasan, and Erik Torenberg

AI Content and the War for Your Attention

Antonio Garcia Martinez, and Chris Hayes

Balaji Srinivasan: How AI Will Change Politics, War, and Money

Martin Casado, and Balaji Srinivasan

Ben and Marc on New Media: Podcasts, Politics & the Collapse of Trust

Marc Andreessen, Erik Torenberg, and Ben Horowitz

Critical Minerals: Mining for the Industrial Future

Turner Caldwell, Ryan McEntush, and Erin Price-Wright

The Future of Software Development - Vibe Coding, Prompt Engineering & AI Assistants

Jennifer Li, Martin Casado, and Matt Bornstein

Marc Andreessen and Joe Lonsdale on Tariffs and Trade

Marc Andreessen, and Joe Lonsdale

America's Energy Problem: The Grid That Built America Can’t Power Its Future

David Ulevitch, Ryan McEntush, and Erin Price-Wright

Aaron Levie on AI's Enterprise Adoption

Aaron Levie, and Martin Casado

Ben Horowitz: What Founders Must Know About AI and Crypto

Tom Bilyeu, and Ben Horowitz

Stablecoins & the Future Financial System

Ali Yahya, Adrianna Simpson, and Erik Torenberg

How Andreessen Horowitz Disrupted VC & What’s Coming Next

Erik Torenberg, Marc Andreessen, and Ben Horowitz

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Bio Eats World

From the latest scientific advances to the biggest trends, this show explores all the ways biology is today where the computing revolution was 50 years ago.

16 Minutes on the News

A short news podcast where we cover the top headlines of the week, the a16z podcast way—why these topics are in the news; what’s real and what’s hype.