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What the Merge Means for Ethereum

Danny Ryan, Jeff Benson, and a16zftr

The Ethereum Foundation's Danny Ryan discusses how the Merge will increase security and explains how proof of stake impacts developers.

Jason Fried on Why He Doesn’t Do Planning or Politics at Work

Jason Fried, Lauren Murrow, and a16zftr

The Basecamp and HEY founder discusses the power of short-term thinking, his framework for startup longevity, and the key thing he looks for when hiring remote.

How to Build a GPT-3 for Science

A GPT-3-like AI model for science would accelerate innovation and improve reproducibility. Creating it will require us to unlock scientific publications.

Why Developers Are Building So Many Side Projects

Ben Stokes and a16zftr

From unleashing creativity to mitigating risk, Ben Stokes of Tiny Projects shares some of the main reasons why developers are building so many side projects.

What’s After Proof of Stake for Ethereum?

Danny Ryan, Jeff Benson, and a16zftr

Danny Ryan details the path forward for scalability and explains the possibility of stateless Ethereum, while sharing how the Merge will affect future upgrades.

Why Applying Machine Learning to Biology is Hard – But Worth It

Jimmy Lin and Nicole Neuman

Did We Overeat on Software?

Andrej Safundzic and a16zftr

Our Cities Have an API Problem. Startups Can Fix It.

Zach Caceres and a16zftr

Research Twice, Build Once: How to Know Your Users as You Grow

Ryan Glasgow and a16zftr

Grow or Die: A Framework for Turning Your Company Around Fast

Michael Mignano and a16zftr

What Synthetic Embryos Can and Can’t Do, Now and in the Future

Magda Zernicka-Goetz and Nicole Neuman

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The Two Things We’ll Need for the Next AlphaFold

Daphne Koller and Nicole Neuman

A Guide to Decentralized Biotech

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What Is Negative Engineering?

Jeremiah Lowin and a16zftr

How to Use Massive AI Models (Like GPT-3) in Your Startup

Elliot Turner and a16zftr

PlanetScale CEO on Cloud-Prem and Climbing the Engineering Ladder

Sam Lambert, Derrick Harris, and a16zftr

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What the Merge Means for Ethereum

Danny Ryan, Jeff Benson, and a16zftr

Info Diet: a16z Crypto’s Elena Burger

Elena Burger and a16zftr

7 Essential Ingredients of a Metaverse

Liz Harkavy, Eddy Lazzarin, and Arianna Simpson

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Data50: The World’s Top 50 Data Startups

Jennifer Li, Sarah Wang, Jamie Sullivan, and a16zftr

Why SQL Needs Software Libraries

George Fraser, Derrick Harris, and a16zftr

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Innovation & Creativity

The Future of Search Is Boutique

Sari Azout and a16zftr

AlphaFold, GPT-3 and How to Augment Intelligence with AI (Pt. 2)

Niko Grupen and a16zftr

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Leadership & Management

How to Make Talent Scouts Work for You

Tyler Cowen, Daniel Gross, and a16zftr

Cloud Wars & Company Wars: Play Nice, But Win

Michael Dell, Marc Andreessen, Martin Casado, and Sonal Chokshi

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Sales & Go to Market

Sales Enablement: The Underrated Cog of Enterprise Commercial Engines

Vassilis Tziokas and a16zftr

Product-Market Sales Fit (What Comes First?)

Jyoti Bansal, Peter Levine, Satish Talluri, and Sonal Chokshi

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The Marketplace 100: 2022

Olivia Moore, Brandon Barros, and a16zftr

Hopper CEO on Super-App Ambitions and Becoming an Everything Startup

Frederic Lalonde and Theresa Fisher

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How Recommendation Algorithms Actually Work

The Future of Kidtech: A Web Browser for the Under-10 Set

Keith Schacht and a16zftr

Unbundling Digital Identity Unlocks New Ways to Play and Build

Jon Radoff and a16zftr

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