Featured Episodes

Textiles as Tech, Science, Math, Culture, or Civilization

Virginia Postrel and Sonal Chokshi

AI, WebRTC, Crypto, and Full Stack Startups

Elad Gil, Sep Kamvar, and Chris Dixon

Feedback Loops — Company Culture, Change, and DevOps

Nicole Forsgren, Jez Humble, and Sonal Chokshi

Latest Episodes

David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion

David George, and Jack Altman

Beyond the God Model | Alex Atallah & Amjad Masad

Erik Torenberg, Amjad Masad, and Alex Atallah

Why AI Agents Can Beat the Incumbents

Elena Burger, Seema Amble, and Vladimir Keil

Rebuilding the Internet for Privacy | Barrett Lyon on DoxxNet

Joel de la Garza, and Barrett Lyon

The $1 Trillion AI Buildout | State of Markets

David George, Sarah Wang, Alex Immerman, and Santiago Rodriguez

The Personal Agent Race Is Here | Anish Acharya & David Pawlan

Anish Acharya, and David Pawlan

AI Can Write Code. Why Isn’t Software Better?

Ben Horowitz, Martin Casado, and Diogo Almeida

Building a Team at AI Speed | Harvey’s Maggie Landers

Katie Kirsch, and Maggie Landers

Aaron Levie, Steven Sinofsky & Martin Casado: How Do You Secure a World of AI Agents?

Erik Torenberg, Martin Casado, Steven Sinofsky, and Aaron Levie

The Reputation Graph of Silicon Valley | Introducing Cosign

Erik Torenberg, Josh Elman, Olivia Moore, and David Booth

The Case Against an AI Pause | Eddy Lazzarin

Theo Jaffee, and Eddy Lazzarin

Amjad Masad on Rethinking College for the AI Era

Erik Torenberg, Amjad Masad, and Gagan Biyani

Why a16z is Building a New School for the AI Era | Ben Horowitz

Ben Horowitz, Gagan Biyani, and Erik Torenberg

AI Safety Language Is Destroying the Debate | Steven Sinofsky

Steven Sinofsky, Theo Jaffee, and Sofia Puccini

Nas, Grandmaster Caz, Steve Stoute & Ben Horowitz on Paying Hip-Hop’s Pioneers Their Due

Ben Horowitz, Erik Torenberg, Nas, Steve Stoute, and Grandmaster Caz

What Makes a Consumer AI Product Stick? | Josh Elman

Josh Elman, and Ollie Forsyth

Databricks CEO on AI Pacing, Cyber Risk, and the Enterprise

Sarah Wang, Martin Casado, and Ali Ghodsi

The Next Frontier of AI Video Is Control

Jennifer Li, Gorkem Yurtseven, and Batuhan Taskaya

The AI-Native CRM

Joe Schmidt, Alex Rampell, and Keith Peiris

The Age of Body Futurism | Ruby Justice Thelot

Elena Burger, and Ruby Justice Thelot

Greg Brockman on Why OpenAI Says We’re Entering the AGI Era

Ben Horowitz, Erik Torenberg, and Greg Brockman

World Models, Robotics, and the Future of 3D AI

Theo Jaffee, Sofia Puccini, and Justin Johnson

Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast

Anish Acharya, and Lenny Rachitsky

What It Takes to Build a Startup | Andrew Chen & Matt Perault

Matt Perault, and Andrew Chen

How AI Is Rewriting the Power Law of Venture Capital

Jen Kha, David George, and Aram Verdiyan

Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan

Ben Horowitz, Erik Torenberg, Jennifer Li, and Rayan Krishnan

OpenAI Researchers on the Future of Mathematical Reasoning

Lisha Li, Mehtaab Sawhney, and Mark Sellke

Can Open Source Keep AI Power From Concentrating?

Sophia Dew, and Lukasz Kaiser

Your AI Doctor Is Coming | Julie Yoo

Julie Yoo, and Sophia Dew

Aaron Levie on Why Open AI Wins

Theo Jaffee, Sofia Puccini, and Aaron Levie

Fei Fei Li: The Race to Build World Models For AI

Martin Casado, Fei-Fei Li, Justin Johnson, and Ben Mildenhall

The $100B Niches Hiding Inside Payments

Erik Torenberg, Alex Rampell, and Max Levchin

Inside Moderna’s Personalized Cancer Vaccine

Jorge Conde, and Stéphane Bancel

Daniel Litt: The Mathematician's Guide to AI

Lisha Li, and Daniel Litt

Gavin Baker: Why AI Demand Is Outrunning Compute Supply

David George, and Gavin Baker

Why a16z Launched the Machine Age Fund | Jen Kha

Jen Kha, Theo Jaffee, and Sophia Dew

Why 1,200 AI Agents Started Working Together | Ryan Greenblatt

Theo Jaffee, and Ryan Greenblatt

The Infrastructure Behind the Machine Age

Ben Horowitz, Erik Torenberg, Martin Casado, and Raghu Raghuram

Inside Cursor: The Anatomy of a Generational Startup

Martin Casado, Sarah Wang, and Matt Bornstein

The State of AI: Macro, Apps, and Consumer

Anish Acharya, and Jen Kha

The New Economics of AI | Martin Casado & Steven Sinofsky

Erik Torenberg, Martin Casado, and Steven Sinofsky

Why Medical AI Needs a Referee | Protege's Engy Ziedan

Daisy Wolf, Eva Steinman, and Engy Ziedan

Martin Casado on Where the Value Is Going in AI

Martin Casado, Theo Jaffee, and Sophia Dew

Microsoft's Deputy CISO on Securing AI Agents

Joel De La Garza, and Aaron Zollman

How Global Networks Are Reshaping Startup Success

Elena Burger, Angela Strange, and Gabriel Vasquez

How Whatnot Built a Global Marketplace

David George, and Grant LaFontaine

How Do You Defend Against AI That Can Hack?

Joel de la Garza, Nick Warner, and Max Pollard

Stripe’s AI Strategy: Build More, Not Less

David George, and Will Gaybrick

Ben Horowitz and Travis Kalanick on Building Again

Erik Torenberg, Ben Horowitz, and Travis Kalanick

The Two Ways to Sell AI: Lighthouse or Landgrab?

Elena Burger, Joe Schmidt, and Andy McCall

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A short news podcast where we cover the top headlines of the week, the a16z podcast way—why these topics are in the news; what’s real and what’s hype.