Featured Episodes

Textiles as Tech, Science, Math, Culture, or Civilization

Virginia Postrel and Sonal Chokshi

AI, WebRTC, Crypto, and Full Stack Startups

Elad Gil, Sep Kamvar, and Chris Dixon

Feedback Loops — Company Culture, Change, and DevOps

Nicole Forsgren, Jez Humble, and Sonal Chokshi

Latest Episodes

How Radiant and Heron Are Rethinking Power Generation and Delivery

Erik Torenberg, Erin Price-Wright, Drew Baglino, and Doug Bernauer

Marc Andreessen on Evaluating Founders and AI's Consumer Surplus

Marc Andreessen, and Harry Stebbings

The SpaceX and Tesla Playbook for Hard Tech Startups

Erin Price-Wright, Chandler Luzsicza, and Turner Caldwell

Security, Resilience, and the Future of Mobile Infrastructure

David Ulevitch, John Doyle, and Justin Fanelli

Submarines and the Future of Defense Manufacturing

David Ulevitch, VADM Robert Gaucher, and Chris Power

The Missing Power Layer of Modern Warfare

Erin Price-Wright, Alex Miller, and Adam Warmoth

Why Every Satellite Needs Earth | Northwood CEO on a16z

Erik Torenberg, and Bridgit Mendler

Inside Palantir: Building Software That Matters with Shyam Sankar

Shyam Sankar, Erik Torenberg, and Katherine Boyle

AI Just Gave You Superpowers — Now What?

Robert Hackett, Eddy Lazzarin, and Christian Catalini

AI, Supply Chains, and the Future of Economic Power

Erik Torenberg, and Jacob Helberg

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

Vishal Misra, and Martin Casado

AI Startups vs. Big Chatbots — With Olivia Moore

Olivia Moore, and Alex Kantrowitz

Marc Andreessen on the Mindset of Great Founders — with David Senra

Marc Andreessen, and David Senra

Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon

Emil Michael, and David Ulevitch

Palantir CEO Alex Karp on the Zero-Sum AI Race

Alex Karp, and Katherine Boyle

What It Takes to Clear a Million Crimes a Year with Flock Safety's CEO

Garrett Langley, and John Collison

The Top 100 Gen AI Consumer Apps

ai, artificial intelligence, movies, agents, and media

Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Andrew Huberman, and Daisy Wolf

Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

Alex Rampell, Erik Torenberg, and Mike Cannon-Brookes

Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power

Ben Thompson, John Coogan, and Jordi Hays

Deploying AI in Healthcare

Julie Yoo, and Nikhil Buduma

Ben Horowitz On What Makes a Great Founder

Ben Horowitz, and Brian Halligan

Chris Dixon: From Quant Trading to Building a16z Crypto

Chris Dixon, and Brian McCullough

a16z's New Media Playbook

Erik Torenberg, Ben Horowitz, and Marc Andreessen

When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market

Joe Weisenthal, Tracy Alloway, and David George

Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics

Peter H. Diamandis, Ben Horowitz, Salim Ismail, Dave Blundin, and Dr. Alexander Wissner-Gross

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Patrick Collison, and Michael Truell

AI’s Capital Flywheel: Models, Money, and the Future of Power

Alessio Fanelli, and Swyx (Shawn Wang

From Copilots to Agents: Rebuilding the Company Around AI

Carlos García Ottati, Gabriel Vasquez, and Angela Strange

WSJ x a16z: The Next 25 Years of Defense Innovation

Katherine Boyle, and Andy Serwer

Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company

Vasant Narasimhan, and Jorge Conde

Balaji and Dan Wang: The Engineering State vs Lawyerly State

Dan Wang, and Balaji Srinivasan

Anish Acharya: Is SaaS Dead in a World of AI?

Harry Stebbings, and Anish Acharya

How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years

Magic Johnson, and Chris Lyons

Marc Andreessen: Who Runs the World’s AI?

Marc Andreessen, and Jeetu Patel

The State of Markets

Jen Kha, and David George

Balaji & Benedict Evans: When Tech Breaks Industries

Balaji Srinivasan, and Benedict Evans

Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES

Tim Higgins, Martin Casado, and Christopher Mims

Why America’s Health Crisis Is an Incentive Problem

Justin Mares, and Erik Torenberg

Palmer Luckey on Hardware, Building, and the Next Frontiers of Innovation

Chris Dixon, and Palmer Luckey

David Solomon & Ben Horowitz on Building Organizational Resilience & Navigating Macro Uncertainty

David Haber, David Solomon, and Ben Horowitz

“Anyone Can Code Now” - Netlify CEO Talks AI Agents

Matt Biilmann, Martin Casado, and Erik Torenberg

Marc Andreessen on Why This Is the Most Important Moment in Tech History

Marc Andreessen, and Lenny Rachitsky

Ben Horowitz and Balaji Srinivasan on Netscape and Network States

Ben Horowitz, and Balaji Srinivasan

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

Jay Rughani, and Nikhil Krishnan

The Hidden Economics Powering AI

Jen Kha, and David George

How Mintlify Is Rebuilding Documentation for Coding Agents

Han Wang, Hahnbee Lee, Jennifer Li, and Yoko Li

Inferact: Building the Infrastructure That Runs Modern AI

Woosuk Kwon, Simon Mo, and Matt Bornstein

Martin Casado on the Demand Forces Behind AI

Patrick Moorhead, Daniel Newman, and Martin Casado

From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu

Beyang Liu, Martin Casado, and Guido Appenzeller

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Bio Eats World

From the latest scientific advances to the biggest trends, this show explores all the ways biology is today where the computing revolution was 50 years ago.

16 Minutes on the News

A short news podcast where we cover the top headlines of the week, the a16z podcast way—why these topics are in the news; what’s real and what’s hype.